Up and down states

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Cell-type specific modulation of neocortical UP and DOWN states

Citation: Ramaswamy S and Muller EB (2015) Cell-type specific modulation of neocortical UP and DOWN states. The mammalian brain is continuously active. Even during sleep and anesthesia, a rich spectrum of spontaneous oscillatory activity occurs in neocortex. A prominent example of such rhythmic activity is the emergence of so-called UP and DOWN states in neocortical networks. UP states are plat...

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Irregular Dynamics in Up and Down Cortical States

Complex coherent dynamics is present in a wide variety of neural systems. A typical example is the voltage transitions between up and down states observed in cortical areas in the brain. In this work, we study this phenomenon via a biologically motivated stochastic model of up and down transitions. The model is constituted by a simple bistable rate dynamics, where the synaptic current is modula...

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The Emergence of Up and Down States in Cortical Networks

The cerebral cortex is continuously active in the absence of external stimuli. An example of this spontaneous activity is the voltage transition between an Up and a Down state, observed simultaneously at individual neurons. Since this phenomenon could be of critical importance for working memory and attention, its explanation could reveal some fundamental properties of cortical organization. To...

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Markov Repairable Systems with History-Dependent Up and Down States

This paper introduces a Markov model for a multi-state repairable system in which some states are changeable in the sense that whether those physical states are up or down depends on the immediately preceding state of the system evolution process. Several reliability indexes, such as availability, mean up time, steady-state reliability, are calculated using the matrix method. A sufficient condi...

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Differential responses of hippocampal subfields to cortical up-down states.

The connectivity of the hippocampal trisynaptic circuit, formed by the dentate gyrus, the CA3 and the CA1 region, is well characterized anatomically and functionally in vitro. The functional connectivity of this circuit in vivo remains to be understood. Toward this goal, we investigated the influence of the spontaneous, synchronized oscillations in the neocortical local field potential, reflect...

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ژورنال

عنوان ژورنال: Scholarpedia

سال: 2008

ISSN: 1941-6016

DOI: 10.4249/scholarpedia.1410